stiripentol will enhance the stage or impact of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep an eye on Closely. Consider cutting down the dose of CYP2C19 substrates, if adverse reactions are knowledgeable when administered concomitantly with stiripentol.
90% of Modafinil metabolizes inside your liver as motionless metabolites into modafinil acid and modafinil sulfone.
rifapentine will reduce the extent or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Prevent coadministration of sensitive CYP3A4 substrates with ivosidenib or exchange with alternative therapies. If coadministration is unavoidable, keep an eye on clients for lack of therapeutic influence of such medicines.
Specific serious Unwanted effects might include things like melancholy, aggression or hostility in the direction of other people or suicidal ideas or other changes in the behaviour. Consult your medical professional right away when you practical experience any this kind of Negative effects.
modafinil will raise the stage or influence of flibanserin by impacting hepatic enzyme CYP2C19 metabolism.
Check Intently (1)modafinil will raise the level or outcome of flibanserin by influencing hepatic enzyme CYP2C19 metabolism.
Mental or mood challenges like depression and suicidal ideas have occurred with modafinil. Often, people necessary to get handled within a hospital. When you've got at any time had any psychological or temper challenges, speak with your physician.
sparsentan will minimize the level or result of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Sparsentan (a CYP2C19 inducer) decreases publicity of CYP2C19 substrates and reduces efficacy connected to these substrates.
fedratinib will enhance the level or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Change dose of medication that are CYP3A4 substrates as important.
Check Closely (two)modafinil will lower the level or effect of diazepam buccal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Potent or moderate CYP3A4 inducers might boost rate of diazepam elimination; hence, efficacy of diazepam could be lowered.
MODALERT 200MG TABLET will not be proposed for use in breastfeeding women as it may well pass through breast milk. Talk to your health practitioner right before getting it.
enasidenib will improve the degree or impact of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Enasidenib (a weak CYP2C19 inhibitor) might enhance systemic exposure of delicate CYP2C19 substrates. Monitor and change dose of substrate as clinically indicated.
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